Subutex 28x 8mg

Subutex 28x 8mg is a prescription medication containing the active substance Buprenorphine, manufactured by Reckitt Benckiser. This medication comes in the form of sublingual tablets, with each tablet containing 8 mg of Buprenorphine. The package includes 28 tablets.

Active Substance: Buprenorphine

Buprenorphine is a partial opioid agonist, meaning it binds to the same receptors in the brain as other opioids but activates them to a lesser degree. This unique mechanism helps alleviate withdrawal symptoms and cravings associated with opioid dependence while reducing the risk of misuse, respiratory depression, and other side effects typical of full opioid agonists.

Indications:

Subutex is indicated for the treatment of opioid dependence. It is used as part of a comprehensive treatment plan that includes counseling and psychosocial support. The medication helps to:

• Suppress withdrawal symptoms: Reduces the discomfort associated with opioid withdrawal.
• Decrease cravings: Helps diminish the desire to use opioids.
• Block the effects of other opioids: Occupies opioid receptors, reducing the effects of other opioids if used concurrently.
• Promote recovery: Supports long-term recovery by stabilizing patients and preventing relapse.

Dosage and Administration:

The dosage of Subutex must be tailored to each patient’s needs. Initial doses typically start under medical supervision to monitor response and adjust accordingly.

• Induction Phase: For patients dependent on short-acting opioid products, Subutex is usually initiated at 4 mg of Buprenorphine, followed by an additional 4 mg if needed on the first day, for a total of 8 mg.
• Maintenance Phase: The dose is adjusted based on the patient’s response and can range from 8 mg to 16 mg per day. The maximum recommended dose is 24 mg per day.

Subutex tablets should be placed under the tongue until fully dissolved. Swallowing or chewing the tablets is not recommended as it reduces the effectiveness.

Key Features:

• Efficacious: Effective in managing opioid dependence, reducing withdrawal symptoms, and cravings.
• Safety Profile: Lower risk of respiratory depression and misuse compared to full opioid agonists.
• Convenient Dosing: Sublingual administration allows for ease of use and consistent absorption.
• Support for Recovery: When combined with counseling and psychosocial support, it significantly enhances the chances of long-term recovery.

Precautions:

• Dependency and Withdrawal: Prolonged use can lead to physical dependence. Tapering off the medication should be done gradually under medical supervision.
• Contraindications: Not suitable for individuals with severe respiratory insufficiency, acute alcoholism, or hypersensitivity to Buprenorphine.
• Interactions: Can interact with other CNS depressants, alcohol, certain antibiotics, antifungals, and medications that affect liver enzymes.
• Pregnancy and Lactation: Should be used with caution during pregnancy and breastfeeding due to potential risks to the fetus and infant.

Side Effects:

Common side effects of Subutex include:

• Headache
• Nausea and vomiting
• Sweating
• Insomnia
• Constipation
• Dizziness

Serious but less common side effects may include:

• Respiratory depression
• Severe allergic reactions
• Liver dysfunction
• Orthostatic hypotension

Storage:

Store Subutex tablets at a temperature between 20-25°C (68-77°F), protected from light and moisture. Keep out of reach of children.

Conclusion:

Subutex 28x 8mg by Reckitt Benckiser is a valuable medication in the treatment of opioid dependence. With its active substance Buprenorphine, Subutex effectively reduces withdrawal symptoms and cravings, supporting patients in their journey towards recovery. It is crucial to use this medication as part of a comprehensive treatment plan under the supervision of a healthcare professional.